Your best bet for blasting belly fat is slow, steady weight loss -- not instant one-week results. Steer clear of diets promising double-digit weight loss in just a week or diets that cut out entire food groups or require you to eat just a couple foods. These are typically fad diets that aren't sustainable -- so you're likely to regain any lost weight -- and such diet plans might even interfere with your ability to lose fat in the long run, explains the University of Wisconsin-Madison.
3. Exercise Ball Crunch: This is one of the most effective ways to strengthen and flatten abs.  Studies show this exercise is 40% more effective than regular ab crunches as it targets smaller muscles for flat toned abs including the oblique’s for a small waist and the outermost muscles that your typical ab crunch may miss.  To begin, lie down on the ball positioning it under the lower back.  Place arms behind your head.  Tighten your abs as you lift your torso off the ball while keeping the ball stable.  Lower back down and repeat 15 times with 1-3 sets.
Ketchup has very little nutritional value as compared to the fruit from which it is derived. But if you’re looking for an alternative for ketchup, salsa is just the sauce to help you lose weight fast and retain the tangy taste. A study conducted at China Medical University in Taiwan suggests that since salsa is made from fresh tomatoes which contain lycopene, it doesn’t just help reduce fat overall but also specifically around the belly. If you like your salsa spicy, it’s even better because the capsicum in hot peppers like jalapenos and chipotle will help you boost metabolism and in turn reduce weight.
Yeah, it might be a bit much – but it’s just what I’ve always done and I think part of it might be from habit – plus, as I stated, I am still able to make progress – slow, but some progress anyways. I will try and stretch out my deload spacing to maybe 6 or 8 weeks. Part of the problem is that this winter (I live in Chicago) has been long and cold – which isn’t fun when working out in a garage at 5 a.m. – I think that all by itself might be causing part of the sore/dragging/worn-out feeling (which I usually associate with a need to deload). Maybe my body will rebound here in the spring and I can space my deloads out more. Thanks.
It's easy to overdo it when you're eating something delicious — and that's why it's good to focus on foods that will force you to slow down. "Slowing down can help you check in with your hunger levels. For that reason, I love snacking on 100-calorie packs of in-shell pistachios," Gorin says. "Shelling the pistachios helps you slow down your snacking, and the shells leave a visual cue to remind you of how much you've eaten. Because you're more in tune with what's gone into your mouth, you may be less likely to have extra servings." In one preliminary study, people snacking on in-shell pistachios ate 41% less calories than those who ate the shelled version.
Squats are really great exercises for your buttocks and legs. Squat is a position in which you couch or sit with knees bent close to the heels with your thighs parallel to the floor. It is a full body work out that primarily targets hips, thighs and buttocks. If you find this exercise routine difficult then try the same sitting on a chair and standing up, now repeat this process a number of times to tone your body and provide some benefit to it.
Having support is very important with weight loss. If everyone can get on board, it will be easier to achieve your goals. Talk to your family (or friends, roommates, etc) before starting your diet and let them know your plan. Explain why you are making this decision and ways they can help you succeed. Even if they do not change with you, that's okay! Go forward with your plan! They may decide to join you once they see you succeed with weight loss.
“I would focus on proteins from lean and minimally processed sources, two weekly servings of fish, carbohydrates from starchy vegetables, fruits, and legumes, and fats from plant-based sources,” says Feller. You’ll also want to stay seriously hydrated, as “water may help fill you up,” says Gans. Studies show that drinking just two glasses of water before a meal can help you consume less calories, and drinking throughout the day can keep you from misinterpreting thirst cues as hunger pangs.
Fighting constantly with your S.O.? It’s time to address your issues head-on. "Research has shown that cortisol, the hormone that's released during stressful activity, is linked to fat storage,” says Gina Guddet, couples counselor and co-author of Love Metabolism. “And poor communication between couples is the most common type of stress that you tend to experience."
In what is perhaps the biggest buzzkill of all time, sex doesn’t quite count as cardio or burn a significant amount of calories: Women burn about 3.6 per minute. “It’s still a good idea,” Dr. Seltzer says, citing the activity’s other benefits, like increasing the output of the neurotransmitters serotonin and dopamine, which naturally reduce food cravings.
This drug is an injected variant of a satiety hormone called GLP-1. It slows down how quickly the stomach empties and tells the brain that you don’t need to eat yet – a great idea for losing weight. As a bonus this drug works fine while one is on the keto diet and it works even better with intermittent fasting – for a rapid weight loss with no hunger.
You’ve heard of a self-fulfilling prophecy? If you keep focusing on things you can’t do, like resisting junk food or getting out the door for a daily walk, chances are you won’t do them. Instead (whether you believe it or not) repeat positive thoughts to yourself. “I can lose weight.” “I will get out for my walk today.” “I know I can resist the pastry cart after dinner.” Repeat these phrases and before too long, they will become true for you. Try these other daily mantras that can help you reach your goals.
"With all the different tips out there, it can be tricky to understand exactly which exercises work the best. HIIT is great for fat burning and will get your heart rate up, but I’d also recommend including strength (resistance) exercises too. Try lifting weights, using resistance bands or using the weight machines at the gym as these will increase your metabolism to help with weight loss, and increase your muscle strength. It’s important to mix-up your whole-body workouts so you don’t get bored."
2. Log your food intake in a journal, or app for 3 days – When you track your eating habits with a food journal, or calorie tracking app even for a few days, it will be an eye-opening experience that can increase your body awareness and help you change your habits.8 You will learn how many calories you are eating each day, and also the calories in the foods you normally eat. Understanding your current habits will make changing them much more manageable, and can help you keep weight off long-term.9

74. Practice Breathing Or Meditation First Thing In The Morning – Did you know you can control your central nervous system with your breath? It almost sounds like a ninja training trick, but you can actually do it too. Practice a breathing exercise, like crocodile breathing, for 5 minutes any time you’re stressed or before going to bed. Alternatively, you can try meditation, which is associated with increased mindfulness and productivity, decreased stress, and improved weight management. Increasing your body awareness through breath or meditation can make you more aware of your hunger and satiety cues, meaning increased weight loss.60
Avoiding salt doesn’t mean your food has to be bland. Experiment with using different herbs and spices. Try adding fresh cilantro and cumin to grilled fish, lemon and rosemary to chicken, or ginger and Chinese five spice to tempeh or beef. Pick up some spice blends from your local market to help add more spice to your life… just read the ingredients and make sure there’s no salt added.

Avoid fad diets. It's never a good idea to trade meals for shakes or to give up a food group in the hope that you'll lose weight — we all need a variety of foods to get the nutrients we need to stay healthy. Avoid diet pills (even the over-the-counter or herbal variety). They can be dangerous to your health; besides, there's no evidence that they help keep weight off over the long term.
You don’t have to be the next Usain Bolt in the making to enjoy some serious belly-slimming results from hitting the track from time to time. Even a moderate-rate jog a few times a week can blast through that belly fat; in fact, a study conducted at Duke University Medical Center found that, over the course of an eight-month study, overweight adult study subjects who jogged 12 miles a week lost the most belly fat and burned 67 percent more calories than participants who did an equivalent amount of resistance exercise, or a combination of cardio and resistance work.
The good news is that there’s increasing evidence that the brain can, in large part, “fix” itself once new behavior patterns emerge (i.e., calorie restriction, healthy food choices, and exercise). While there may be some degree of “damage” to the brain, particularly in how hunger and satiety hormones function, it can correct itself to a large degree over time. The key is that the process does take time, and like any other behavior change, is ultimately a practice. “We want to change behavior here,” says Hill. “Anyone that tells you it’s going to happen in 12 weeks, that’s bogus. We’re trying to rewire the brain. Neurobiology has told us so much about what’s going on in weight gain and weight loss. It takes a long time to develop new habits, rituals, routines. This takes months and years. But it will happen.”
Call it what you will: An eating plan, a lifestyle, a diet, a philosophy, but few things garner such heated debate as how to lose weight. The truth is, whether you’re on a low-carb keto program, devoted to the Paleo lifestyle, all in to the Whole 30 or remain committed to low-fat eating, these plans have more in common than you think. What’s more, follow any one of them religiously, and you’ll likely notice results.
Cherries have several health benefits. They are a good source of antioxidant pigment resveratrol, a substance that helps you lose weight, lowers rates of macular degeneration among older people as well as the risk of dementia. According to the data collected from a study at the University of Michigan, rats that were provided with high-fat food along with tart cherries lost nine per cent more body fat than those in a control group did over just 12 weeks.
So boiling it down even further: reduce calories, eat better, exercise, and most of all, remember it is a practice that has to be repeated over time – months or years. The fact that you'll have to work harder at maintenance than your never-overweight best friend is depressing, but it's worth coming to terms with. And, most important to remember, your brain (the organ behind all this, after all) is plastic, and it will respond to the changes you make – better than you think. And so will your body.
The causal relationship between diets and weight gain can also be tested by studying people with an external motivation to lose weight. Boxers and wrestlers who diet to qualify for their weight classes presumably have no particular genetic predisposition toward obesity. Yet a 2006 study found that elite athletes who competed for Finland in such weight-conscious sports were three times more likely to be obese by age 60 than their peers who competed in other sports.
Compare your portion sizes throughout the day to the recommended standards. For example, one serving of fruit is 1/2 cup or one small whole fruit, one serving of vegetables is one cup, one serving of grains is 1 oz or 1/2 of a cup, one serving of lean protein is 3 oz and one serving of low-fat dairy is one cup (milk and yogurt) or 2 oz of cheese.[5]

Red wine can actually be good for your health, thanks to the antioxidant resveratrol, which studies have shown is good for your health and could help you lose weight. But any more than one glass, and you’re opening yourself up to extra sugar, empty calories, and a boozy buzz, which may inhibit your ability to make healthy food choices. If you’re out to happy hour, stop at one glass and opt for club soda (which is calorie free) or water with lemon instead.
Don’t buy your tickets to Bonnaroo just yet; the kind of acid that will help you slim down is the stuff right inside your cabinet. A 12-week study published in Bioscience, Biotechnology, and Biochemistry reveals that obese study subjects who made vinegar part of their diet dropped more belly fat than a control group, and other research suggests that acidic foods, like vinegar, can increase the human carbohydrate metabolism by as much as 40 percent.

Berries contain antioxidants that help reduce inflammation throughout the body. According to a University of Michigan research, rats who were fed a diet rich in berries, shaved off a substantial amount of belly fat in comparison to a control group. Strawberries, raspberries, blueberries and blackberries are loaded with resveratrol, the antioxidant pigment which is known to help you lose weight.

Instead of satisfying your sweet tooth with some refined sugar, turn to berries and enjoy a slimmer waistline in no time. Berries are loaded with antioxidants, which can help reduce inflammation throughout the body, and research from the University of Michigan reveals that rats given a berry-rich diet shaved off a significant proportion of their belly fat when compared to a control group. Berries like strawberries, raspberries, blueberries, and blackberries are also loaded with resveratrol, an antioxidant pigment that has been linked to reductions in belly fat and a reduced risk of dementia, to boot.

Eating sugary foods might be satisfying in the moment, but they can increase your cravings for more sugary foods in the future — and that only leads to trouble. "Many foods high in added sugar are also higher in calories and fill you up less than lower-calorie, still-sweet alternatives like fruit," says Amy Gorin, MS, RDN, owner of Amy Gorin Nutrition in Jersey City, NJ. But there are still ways to satisfy your sweet tooth without ODing on sugar. "When you're baking, cut out some of the sugar in recipes by adding in vanilla extract or cinnamon, blend unsweetened cocoa powder into a smoothie instead of honey, top your French toast with unsweetened frozen fruit instead of syrup, and nosh on a slab of watermelon instead of cookies."
"One of the hardest parts of losing weight is maintaining the lifestyle changes you’ve made. It’s difficult to stay motivated all the time, especially if you’ve slipped up along the way. But don’t let this affect your end goal. If you’re feeling particularly unmotivated, ask a friend to join you for your workout and then afterwards cook something healthy for dinner together."
55. Have 1 Healthy Snack At Work Per Day – Bringing a snack to work eliminates the temptation to buy less healthy options. Some great choices include an apple, hummus and veggies, hardboiled eggs, turkey jerky, or plain greek yogurt with berries. This should help keep your energy levels high while keeping your hunger under control until dinner time. Here are 25 awesome snack ideas to choose from.
My repeated dieting eventually caught up with me, as this research would predict. When I was in graduate school and under a lot of stress, I started binge eating. I would finish a carton of ice cream or a box of saltines with butter, usually at 3 a.m. The urge to keep eating was intense, even after I had made myself sick. Fortunately, when the stress eased, I was able to stop. At the time, I felt terrible about being out of control, but now I know that binge eating is a common mammalian response to starvation.

But it's important to remember that "fat" doesn't mean "unhealthy." Yes, women have larger fat stores, but it's part of their physiology, meaning it's not extra weight. So if a woman has 11 percent more body fat than a man, it doesn't mean she's 11 percent "fatter." A perfectly fit woman will still hold six to 11 percent more body fat than a perfectly fit man.
He's laughing at you - all of you, and he knows that all he has to do is stay fat and you'll loving care for him. Being fat is his job but when he gets bored with it - and he will, you will be the ones he blames.Nobody forced him to become the pig he is. if you pander to him he will just continue. He isn't ill, and definitely not stupid. He doesn't deserve compassion but desperately needs tough love.Kick him out on the street, he's had enough free service now it's time to pick up the tab.If he lives, he lives - if he dies, dies. I, nor anybody else truly cares

People who are normal weight, or overweight and do not have any additional risk factors for heart disease, should focus on avoiding weight gain, rather than losing weight, the guidelines say, because there is no strong evidence that weight loss provides health benefits for these people. However, additional weight gain could lead to problems, experts said.

If not bothersome I’d like to ask you a specific question that I don’t believe I’ve seen on your website. I know the sole factor of fat loss is calorie deficit and am happy with the weight loss I’ve achieved in the past 9 weeks. I will attend a friend’s wedding for a week next week and don’t imagine I will be able to maintain my current diet. I’ve read from other sources discussing how you should “SLOWLY” increase your calorie consumption to avoid your body storing fat. I will certainly not eat 4,000 calories during my trip but my question will be if it’s OK for me to jump back to “maintenance level” calorie consumption or you would recommend me doing “15% Deficit on Day 1, 10% Deficit on Day 2…etc.”?
SIX years after dropping an average of 129 pounds on the TV program “The Biggest Loser,” a new study reports, the participants were burning about 500 fewer calories a day than other people their age and size. This helps explain why they had regained 70 percent of their lost weight since the show’s finale. The diet industry reacted defensively, arguing that the participants had lost weight too fast or ate the wrong kinds of food — that diets do work, if you pick the right one.
Chapter 10 talks all about self love, and I agree it is extremely important to have. I lost a lot of respect though because it starts off saying how people who are overweight have a lack of self esteem and look down on themselves viewing themselves as inferior...um, you spent a portion of this book shaming obese people and making generalizations. You treated obese people differently and shamed them then wonder why they have low self esteem or don't feel like they fit in. This chapter meant a whole lot less to me coming from you after reading the rest of book. In this chapter while talking about self love, you spend the whole time blaming the person for their own low self esteem. Telling them that everyone has flaws (so you just told this person they are flawed, with the assumption you're talking about being overweight as a flaw because that's what the book is about and it's already obvious you look down on obese people based on your language throughout the book.)
Call it what you will: An eating plan, a lifestyle, a diet, a philosophy, but few things garner such heated debate as how to lose weight. The truth is, whether you’re on a low-carb keto program, devoted to the Paleo lifestyle, all in to the Whole 30 or remain committed to low-fat eating, these plans have more in common than you think. What’s more, follow any one of them religiously, and you’ll likely notice results.

Keep a calculator handy. To calculate your waist-to-hip ratio accurately, measure the narrowest point of your waist and the broadest part of your hip. Divide the values you obtained from the measurement and you have your ratio. The waist-to-hip ratio is a more accurate parameter to measure BMI. Those with a waist-to-hip ratio of 0.8 are susceptible to cardiovascular disease and stroke.


Close the Kitchen at Night. Establish a time when you will stop eating so you won't give in to the late-night munchies or mindless snacking while watching television. "Have a cup of tea, suck on a piece of hard candy or enjoy a small bowl of light ice cream or frozen yogurt if you want something sweet after dinner, but then brush your teeth so you will be less likely to eat or drink anything else," suggests Elaine Magee, MPH, RD, WebMD's "Recipe Doctor" and the author of Comfort Food Makeovers.


“A study published in Nutrition Journal found that participants who ate foods high in monounsaturated fats for lunch (in this case, half an avocado) reported a 40 percent decreased desire to eat for hours afterward. Monounsaturated fats from sources like olive oil, nuts and avocados can reduce cholesterol, promote weight loss, even boost memory.” — David Zinczenko, author of the  Zero Belly Cookbook

According to a study conducted on a sample of over 14,000 subjects, brushing after every meal considerably helped reduce weight. Not only does the minty flavor of your toothpaste keep your teeth clean and get rid of the strong belly-slimming garlic stench, it also triggers a Pavlovian response that signals to your brain, indicating the kitchen is closed.
100. See How Much Money You Can Save – Money is motivating. Calculate how much your restaurant and alcohol indulgences are costing you per month and find out just how much you’ll save by cooking at home and drinking less alcohol. Maybe you can use the money you’ll save on restaurant meals and alcohol to plan vacation where you can show off your strong, lean physique.
Once you've lost weight, keeping it off can seem like a never-ending battle. But it's a battle worth fighting, even if you slip sometimes. Trying, even if you don't always succeed, is better than not doing so, scientists say. There's no clear evidence that "yo-yo dieting" — or weight cycling, as researchers call it — is linked with an increased risk of early death or disease, compared with remaining obese, McManus noted. And very few studies report harmful effects of yo-yo dieting.
85. Focus On Following Your Plan, Not Losing Weight – Dieting and focusing solely on weight loss have been found to be big predictors of weight regain.67 Instead, focus on following a workout and nutrition plan. Define your self-worth in ways other than how you look or how much you weigh. Focus on following your plan and your workout goals, like getting stronger, running faster, and being a better athlete overall.
To make sure you don't lose too much, it's important to figure out your goal weight. Since everyone's body is different, your exact goal weight will differ depending on your height, age, activity level, and body type and should best be decided between you and your doctor or other healthcare provider. In general, Jim said your ideal bodyweight can be calculated by your height. For men, it's 106 pounds plus six pounds for every inch over five feet, e.g., if a man is five-foot-eight, his goal weight should be 154 pounds. For women, it's 100 pounds plus five pounds for every inch over five feet, e.g., if a woman is five-foot-four, the ideal weight is 120 pounds.
That said, carrying extra weight around the middle is also tied to increased heart risks, making it arguably unhealthier to be an overweight man than a plus-size woman. Big bellies, it turns out, are a sort of a double-edged sword when it comes to weight loss: They're an extra health risk for men, but give guys the edge when it comes to dropping pounds.
Don’t buy your tickets to Bonnaroo just yet; the kind of acid that will help you slim down is the stuff right inside your cabinet. A 12-week study published in Bioscience, Biotechnology, and Biochemistry reveals that obese study subjects who made vinegar part of their diet dropped more belly fat than a control group, and other research suggests that acidic foods, like vinegar, can increase the human carbohydrate metabolism by as much as 40 percent.
39. Choose Lean Proteins – Chicken, fish, and turkey are excellent high-protein, lower-fat options. These options also have fewer calories, so you can eat bigger portions while still keeping your calories low. Lean protein keeps you feeling fuller longer and helps control your blood sugar, which means fewer cravings for sugary, high-fat foods.41 This doesn’t mean you have to avoid red meat – just be sure to order leaner cuts. For more ideas on good sources of protein, check out our list of Complete vs Incomplete Protein Sources.

Studies found that people who keep food diaries wind up eating about 15 percent less food than those who don’t. Watch out for weekends: A University of North Carolina study found people tend to consume an extra 115 calories per weekend day, primarily from alcohol and fat. Then cut out or down calories from spreads, dressings, sauces, condiments, drinks, and snacks; they could make the difference between weight gain and loss.
Snacking can be a gray area for weight loss. Really think about whether a snack is necessary before eating it. A low-calorie snack can be a good option before or after a work out or if you're feeling very hungry and there's more than two hours until your next meal.[11] To keep your metabolism moving and keep yourself full, you should be eating every three to four hours. That might mean multiple small meals or three meals with snacks in between.
“If weight loss is the goal, I recommend learning how to properly deadlift. Deadlifting recruits more muscle fiber at once than any other exercise. More muscle working equates to more blood flow, an increased heart rate, more metabolic demand and output. It’s compound, multi-joint and more bang for your buck, not to mention you’ll develop an excellent posterior from them.” — Victoria Viola, PN Certified Nutrition Coach, NSCA CPT, Co-Founder, Excelerate Wellness, LLC
As for commercial weight loss programs, the most effective programs are in-person ones, where people regularly meet with a trained health professional, according to the 2013 guidelines. People should look for a program that lets them meet with a registered dietitian, psychologist, exercise specialist or health counselor at least 14 times over a six-month period, the guidelines say. If you can't attend an in-person program, some studies show that programs that use telephone calls, email or text messages to provide feedback on your progress can also help with weight loss.
Is the egg diet effective? There are several versions of the egg diet, all of which involve eating eggs as the main source of protein and restricting other foods. Eggs contain many nutrients, and the diet may help people lose weight. However, they contain no fiber, and they can be high in cholesterol. Find out more about the pros and cons. Read now
If you eat your dinner restaurant style on your plate rather than family style, helping yourself from bowls and platters on the table, you’ll lose weight. Most of us tend to eat an average of 150 percent more calories in the evening than in the morning. You’ll avoid that now because when your plate is empty, you’re finished; there’s no reaching for seconds.
Exercise every day. A week is a short time, so commit to strenuous exercise to reach your goal. An hour of intense cardio will help you burn calories and sweat out some of your water. Just be sure to drink water to replace what comes out in the sweat or your body will be dehydrated. You'll also want to work on your ab muscles, which will help you stand taller and look slimmer. Do exercises that focus on each area of the abs -- upper, lower and obliques.

“It seems so simple, but 45 to 60 minutes of brisk walking every day can do wonders for your metabolism,” Sahmura Gonzalez, a master trainer at Crunch Fitness in New York City, recently told Prevention. “Plus, it ensures that you don’t over-train, which can lead to an over-production of cortisol—a stress hormone that’s been shown to contribute to belly fat.”
Face it, if you want to lose weight over the long haul, your best bet is to make sustainable, long-term lifestyle changes like the nine simple ones this woman made to shed 45 pounds and keep them off. But sometimes life comes at you fast and you need a fast solution. One smart lifestyle change is to eat plenty of veggies—especially for someone looking to lose weight. Vegetables are nutrient-packed and provide plenty of filling fiber with hardly any calories. Plus, non-starchy veggies have a high water content, so they hydrate you while filling you up—the perfect combination for weight loss.

Simply popping a few almonds in your mouth could help you shed pounds, and not just because almonds are better for you than, say, candy. A study published in the Journal of the American Heart Association found that eating 1.5 ounces of almonds a day reduced belly and leg fat. And another study of overweight adults found that people who ate ¼ cup of almonds for 6 months had a 62 percent greater reduction in weight and BMI.
In people, dieting also reduces the influence of the brain’s weight-regulation system by teaching us to rely on rules rather than hunger to control eating. People who eat this way become more vulnerable to external cues telling them what to eat. In the modern environment, many of those cues were invented by marketers to make us eat more, like advertising, supersizing and the all-you-can-eat buffet. Studies show that long-term dieters are more likely to eat for emotional reasons or simply because food is available. When dieters who have long ignored their hunger finally exhaust their willpower, they tend to overeat for all these reasons, leading to weight gain.
Use an adult energy needs calculator to estimate your calorie intake needs; then subtract the 500 to 1,000 calories for weight loss. For example, a 28-year-old woman who is 5 foot, 9-inches tall weighs 175 pounds and is lightly active -- less than an hour a day -- burns about 2,400 calories daily. She'll burn about 2 pounds of fat in a week if she eats 1,400 calories daily, or 1 pound a week if she eats 1,900 calories a day.
Unfortunately, some women are just more prone to carrying weight in their middle instead of their hips and thighs. Sometimes, it’s genetics—maybe your mother was more apple-shaped. Belly fat can also increase around menopause, or for women who have polycystic ovary syndrome (PCOS). Even certain lifestyle habits, from lack of sleep to stress, can make your belly grow. To lose belly fat, talking with a doctor about what other factors may be affecting your weight gain can be a good place to start. From there, you can craft a belly fat busting routine.
Fathi, Y., Faghih, S., Zibaeenezhad, M. J., & Tabatabaei, S. H. (2016, February). Kefir drink leads to a similar weight loss, compared with milk, in a dairy-rich non-energy-restricted diet in overweight or obese premenopausal women: A randomized controlled trial. European Journal of Nutrition, 55(1), 295–304. Retrieved from https://link.springer.com/article/10.1007/s00394-015-0846-9
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